교수소개
 Faculties
교수소개

교수소개

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성명 한경숙 ( 韓庚淑 / KYUNGSOOK HAN )
소속 컴퓨터공학과
E-Mail khan@inha.ac.kr
연구실 전화 032-860-7388
임용일자 1995.03.01
직급 교수
연구실명 바이오컴퓨팅
세부전공 모델링 및 시뮬레이션, 생물정보학
학력  1983.02 서울대학교(학사)/지질학(컴퓨터공학 부전공)
 1985.02 한국과학기술원(석사)/전산학
 1989.04 Univ. of Minnesota(석사(2))/전산학
 1994.05 Rutgers the State Univ. of New Jersey- New Brunswick(박사)/전산학
경력  1985.03~1986.08 한국전자통신연구소/연구원
 1994.08~1995.02 한국전자통신연구원/선임연구원
 2004.09~2005.08 Stanford University / Computational Genomics/방문연구원

연구업적

학위논문

- Compositional Modeling for Spatial Problems, 1994

주요학술논문

- Predicting protein-binding regions in RNA using nucleotide profiles and compositions, BMC SYSTEMS BIOLOGY, 11권 2호, , 2017.
- Data of protein-RNA binding sites, Data in Brief, , 561~563, 2017.
- AN IMPROVED METHOD FOR PREDICTING INTERACTIONS BETWEEN VIRUS AND HUMAN PROTEINS, JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, 15권 1호, , 2017.
- An efficient algorithm for planar drawing of RNA structures with pseudoknots of any type, JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, 14권 3호, , 2016.
- GeneNetFinder2: Improved Inference of Dynamic Gene Regulatory Relations with Multiple Regulators, IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS, 13권 1호, 4~11, 2016.
- PRIdictor: Protein-RNA Interaction predictor, BIOSYSTEMS, 139, 17~22, 2016.
- Assessing protein-protein interactions based on the semantic similarity of interacting proteins, INTERNATIONAL JOURNAL OF DATA MINING AND BIOINFORMATICS, 13권 1호, 75~83, 2015.
- Predicting protein-binding RNA nucleotides with consideration of binding partners, COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 120권 1호, 3~15, 2015.
- PNImodeler: web server for inferring protein-binding nucleotides from sequence data, BMC GENOMICS, 16, , 2015.
- DBBP: database of binding pairs in protein-nucleic acid interactions, BMC BIOINFORMATICS, 15, , 2014.
- Sequence-based prediction of protein-binding sites in DNA: Comparative study of two SVM models, COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 117권 2호, 158~167, 2014.
- 두 가지 유형의 바이오마커를 이용한 파킨슨병의 진단과 신경섬유 경로의 특징 분석, 정보처리학회논문지. 소프트웨어 및 데이터 공학, 3권 10호, 421~428, 2014.
- Prediction of Protein-Protein Interactions Based on Protein-Protein Correlation Using Least Squares Regression, CURRENT PROTEIN & PEPTIDE SCIENCE, 15권 6호, 553~560, 2014.
- Predicting protein-binding RNA nucleotides using the feature-based removal of data redundancy and the interaction propensity of nucleotide triplets, COMPUTERS IN BIOLOGY AND MEDICINE, 43권 11호, 1687~1697, 2013.
- Classification of diffusion tensor images for the early detection of Alzheimer's disease, COMPUTERS IN BIOLOGY AND MEDICINE, 43권 10호, 1313~1320, 2013.
- Database of Protein-Nucleic Acid Binding Pairs at Atomic and Residue Levels, COMMUNICATIONS IN COMPUTER AND INFORMATION SCIENCE , 375, 1865~0929, 2013.
- Scoring Protein-Protein Interactions Using the Width of Gene Ontology Terms and the Information Content of Common Ancestors, COMMUNICATIONS IN COMPUTER AND INFORMATION SCIENCE , 375, 31~36, 2013.
- PPISearchEngine: gene ontology-based search for protein-protein interactions, COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING, 16권 7호, 691~698, 2013.
- KGVDB: a population-based genomic map of CNVs tagged by SNPs in Koreans, BIOINFORMATICS, 29권 11호, 1481~1483, 2013.
- 상호작용 상대방을 고려한 단백질-결합 RNA 염기 예측 기법, 정보과학회논문지 : 컴퓨팅의 실제 및 레터, 19권 5호, 229~234, 2013.
- Random forest를 이용한 단백질에서의 DNA 결합 부위 예측, 정보과학회논문지 : 소프트웨어 및 응용, 39권 7호, 515~522, 2012.
- ModuleSearch: finding functional modules in a protein-protein interaction network, COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING, 15권 7호, 691~699, 2012.
- Modeling the interactions of Alzheimer-related genes from the whole brain microarray data and diffusion tensor images of human brain, BMC BIOINFORMATICS, 13, , 2012.
- Prediction of protein-protein interactions between viruses and human by an SVM model, BMC BIOINFORMATICS, 13, , 2012.
- Prediction of RNA-binding amino acids from protein and RNA sequences, BMC BIOINFORMATICS, 12권 13호, , 2011.
- ModuleSearch: finding functional modules in a protein-protein interaction network, COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING, , , 2011.
- InfarctSizer: computing infarct volume from brain images of a stroke animal model, COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING, 14권 6호, 497~504, 2011.
- HCV 단백질과 상호작용하는 인간 단백질을 예측하기 위한 SVM 모델, 정보과학회논문지 : 컴퓨팅의 실제 및 레터, 17권 4호, 244~248, 2011.
- Qualitative reasoning of dynamic gene regulatory interactions from gene expression data, BMC GENOMICS, 11, , 2010.
- Gene expression data classification using locally linear discriminant embedding, COMPUTERS IN BIOLOGY AND MEDICINE, 40, 802~810, 2010.
- Predicting RNA-Binding Sites in Proteins Using the Interaction Propensity of Amino Acid Triplets, PROTEIN AND PEPTIDE LETTERS, 17권 9호, 1102~1110, 2010.
- A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties of functional gene network, BMC BIOINFORMATICS, 11, , 2010.
- A reliability measure of protein-protein interactions and a reliability measure-based search engine, COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING, 13, 97~104, 2010.
- An ontology-based search engine for protein-protein interactions, BMC BIOINFORMATICS, 11, , 2010.
- Sequence-Based Prediction of Protein-Protein Interactions by Means of Rotation Forest and Autocorrelation Descriptor, PROTEIN AND PEPTIDE LETTERS, 17, 137~145, 2010.
- PseudoViewer3: generating planar drawings of large-scale RNA structures with pseudoknots, BIOINFORMATICS, 25, 1435~1437, 2009.
- BSFINDER: Finding Binding Sites of HCV Proteins Using a Support Vector Machine, PROTEIN AND PEPTIDE LETTERS, 16, 373~382, 2009.
- Finding motif pairs in the interactions between heterogeneous proteins via bootstrapping and boosting, BMC BIOINFORMATICS, 10, , 2009.
- Prediction of binding sites in HCV protein complexes using a support vector machine, LECTURE NOTES IN COMPUTER SCIENCE, 5226 LNCS권 0호, 130~137, 2008.
- Prediction of RNA-Binding residues in proteins using the interaction propensities of amino acids and nucleotides, LECTURE NOTES IN COMPUTER SCIENCE, 5226 LNCS권 0호, 114~121, 2008.
- Predicting key long-range interaction sites by B-factors, PROTEIN AND PEPTIDE LETTERS, 15, 478~483, 2008.
- Prediction of binding motifs in hepatitis C virus NS5A and human proteins, PROTEIN AND PEPTIDE LETTERS, 15권 5호, 494~504, 2008.
- An algorithm for finding functional modules and protein complexes in protein-protein interaction networks, JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, 2008, 1~10, 2008.
- A general computational model for predicting ribosomal frameshifts in genome sequences, COMPUTERS IN BIOLOGY AND MEDICINE, 37, 1796~1801, 2007.
- FSDB: A frameshift signal database, COMPUTATIONAL BIOLOGY AND CHEMISTRY, 31, 298~302, 2007.
- Hepatitis C virus contact map prediction based on binary encoding strategy, COMPUTATIONAL BIOLOGY AND CHEMISTRY, 31, 233~238, 2007.
- Mining Molecular Structure Data for the Patterns of Interactions between Protein and RNA, LECTURE NOTES IN COMPUTER SCIENCE, 4487, 94~101, 2007.
- Comparative Analysis of the Interaction Networks of HIV-1 and Human Proteins, LECTURE NOTES IN COMPUTER SCIENCE, 4488, 339~346, 2007.
- Predicting Binding Sites of Hepatitis C Virus Complexes using Residue Binding Propensity and Sequence Entropy, LECTURE NOTES IN COMPUTER SCIENCE, 4487, 78~85, 2007.
- PRI-Modeler: extracting RNA structural elements from PDB files of protein-RNA complexes, FEBS LETTERS, 581, 1881~1890, 2007.
- 단백질체 데이터 표준화, BIOINFORMATICS AND BIOSYSTEMS, 1권 4호, 190~194, 2006.
- Intracellular expression of the T-cell factor-1 RNA aptamer as an intramer, MOLECULAR CANCER THERAPEUTICS, 5, 2428~2434, 2006.
- Spatial reasoning for collision detection and hardware implementation, LECTURE NOTES IN CONTROL AND INFORMATION SCIENCES, 344, 596~601, 2006.
- Prediction of ribosomal-1 frameshifts in the Escherichia coli K12 genome, LECTURE NOTES IN COMPUTER SCIENCE, 4115, 612~621, 2006.
- Web service for predicting interacting proteins and application to human and HIV-1 proteins, LECTURE NOTES IN COMPUTER SCIENCE, 4115, 631~640, 2006.
- PseudoViewer: web application and web service for visualizing RNA pseudoknots and secondary structures, NUCLEIC ACIDS RESEARCH, 34, W416~W422, 2006.
- Prediction of readthroughs based on the statistical analysis of nucleotides around stop codons, LECTURE NOTES IN COMPUTER SCIENCE, 3991, 276~283, 2006.
- Web service for finding ribosomal frameshifts, LECTURE NOTES IN COMPUTER SCIENCE, 3991, 284~291, 2006.
- Prediction of RNA structures containing pseudoknots, BIOINFORMATICS AND BIOSYSTEMS, Vol. 1, No. 1, 73~81, 2006.
- Identification of the +1 Ribosomal Frameshifting Site of LRV1-4 by Mutational Analysis, ARCHIVES OF PHARMACAL RESEARCH, 28, 956~962, 2005.
- Prediction of Ribosomal Frameshift Signals of User-Defined Models, LECTURE NOTES IN COMPUTER SCIENCE, 3514, 948~955, 2005.
- Prediction of Protein Interactions by the Domain and Sub-cellular Localization Information, LECTURE NOTES IN COMPUTER SCIENCE, 3516, 1024~1027, 2005.
- Online Prediction of Interacting Proteins with a User-Specified protein, LECTURE NOTES IN COMPUTER SCIENCE, 3516, 1028~1031, 2005.
- A Layout Algorithm for Signal Transduction Pathways as Two-Dimensional Drawings with Spline Curves, LECTURE NOTES IN COMPUTER SCIENCE, 3514, 711~718, 2005.
- PSIbase: a database of Protein Structural Interactome map (PSIMAP), BIOINFORMATICS, 21, 2541~2543, 2005.
- Dynamic Visualization of Signal Transduction Pathways from Database Information, LECTURE NOTES IN ARTIFICIAL INTELLIGENCE, 3397, 663~672, 2005.
- DNA Secondary Structures for Probe Design, LECTURE NOTES IN COMPUTER SCIENCE, 3383, 504~507, 2004.
- HPID: The Human Protein Interaction Database, BIOINFORMATICS, 20, 15, 2466~2470, 2004.
- Predicting genes expressed via -1 and +1 frameshifts, NUCLEIC ACIDS RESEARCH, 32, 16, 4884~4892, 2004.
- WebInterViewer: Integrated Framework for Visualizing and Analyzing Molecular Interaction Networks , NUCLEIC ACIDS RESEARCH, 32, 89~95, 2004.
- Isolation of specific and high-affinity RNA aptamers against NS3 helicase domain of hepatitis C virus, RNA-A PUBLICATION OF THE RNA SOCIETY, 10, 1277~1290, 2004.
- Computational Identification of -1 Frameshift Signals, LECTURE NOTES IN COMPUTER SCIENCE, 3036, 334~341, 2004.
- A Database Server for Predicting Protein-Protein Interactions, LECTURE NOTES IN COMPUTER SCIENCE, 3036, 271~278, 2004.
- PairAnalyzer: Extracting and Visualizing RNA Structure Elements formed by Base Pairing, LECTURE NOTES IN COMPUTER SCIENCE, 3036, 279~286, 2004.
- Prediction of Binding Sites in Protein-Nucleic Acid Complexes, LECTURE NOTES IN COMPUTER SCIENCE, 3037, 309~316, 2004.
- Prediction of Protein Functions using Protein Interaction Data, LECTURE NOTES IN COMPUTER SCIENCE, 3037, 317~324, 2004.
- Three-Dimensional Visualization of Protein Interaction Networks, COMPUTERS IN BIOLOGY AND MEDICINE, 34, 127~139, 2004.
- A Fast Layout Algorithm for Protein Interaction Networks, BIOINFORMATICS, 19, 1882~1887, 2003.
- Discovering Interaction Propensities of Amino Acids and Nucleotides from the Protein-RNA Complexes, MOLECULES AND CELLS, 16, 161~167, 2003.
- Mining RNA Structure Elements from the Structure Data of Protein-RNA Complexes, LECTURE NOTES IN ARTIFICIAL INTELLIGENCE, 2843, 349~356, 2003.
- A Genetic Algorithm for Inferring Pseudoknotted RNA Structures from Sequence Data, LECTURE NOTES IN ARTIFICIAL INTELLIGENCE, 2843, 333~340, 2003.
- Computational Analysis of Hydrogen Bonds in Protein-RNA Complexes for Interaction Patterns, FEBS LETTERS, 552, 231~239, 2003.
- Challenges and new approaches in Genomics and Bioinformatics, GENOMICS & INFORMATICS, 1, 1~6, 2003.
- Prevention of passively transferred experimental autoimmune myasthenia gravis by an in vitro selected RNA aptamer, FEBS LETTERS, 548, 85~89, 2003.
- PseudoViewer2: visualization of RNA pseudoknots of any type, NUCLEIC ACIDS RESEARCH, 31, 3432~3440, 2003.
- Complexity Management in Visualizing Protein Interaction Networks, BIOINFORMATICS, 19, 177~179, 2003.
- 도장영상 인식 시스템의 개발, 한국지능정보시스템학회논문지, 9권, 125~137, 2003.
- Visualization of Protein-Protein Interaction Networks using Force-Directed Layout, LECTURE NOTES IN COMPUTER SCIENCE, 2659, 190~200, 2003.
- A Genetic Algorithm for Predicting RNA Pseudoknot Structures, LECTURE NOTES IN COMPUTER SCIENCE, 2659, 130~139, 2003.
- Computational Approach to Structural Analysis of Protein-RNA Complexes, LECTURE NOTES IN COMPUTER SCIENCE, 2659, 140~150, 2003.
- Predicting Protein Interactions in Human by Homologous Interactions in Yeast, LECTURE NOTES IN COMPUTER SCIENCE, 2637, 159~165, 2003.
- Visualization and Analysis of Protein Interactions, BIOINFORMATICS, 19, 317~318, 2003.
- Visualization of RNA Pseudoknot Structures, LECTURE NOTES IN COMPUTER SCIENCE, 2565, 181~194, 2003.
- Simulation studies of the effects of user mobility on the handoff performance of mobile communications, SIMULATION PRACTICE AND THEORY, 10/8, 497~512, 2002.
- Prediction of RNA Pseudoknots - Comparative Study of Genetic Algorithms, GENOME INFORMATICS, 13, 414~415, 2002.
- Protein Interactions in the Whole Human Genome, GENOME INFORMATICS, 13, 318~319, 2002.
- Analysis of Protein-RNA Interactions at Atomic Level, GENOME INFORMATICS, 13, 312~313, 2002.
- A Mobile System for Extracting and Visualizing Protein-Protein Interactions, LECTURE NOTES IN COMPUTER SCIENCE, 2510, 47056, 2002.
- New Representation and Algorithm for Drawing RNA Structure with Pseudoknots, LECTURE NOTES IN COMPUTER SCIENCE, Vol.2454, 191~201, 2002.
- PseudoViewer: automatic visualization of RNA pseudoknots, BIOINFORMATICS, Vol. 18, S321~S328, 2002.
- InterViewer: Dynamic Visualization of Protein-Protein Interactions, LECTURE NOTES IN COMPUTER SCIENCE, Vol.2528, 364~365, 2002.
- A Partitioned Approach to Protein Interaction Mapping, LECTURE NOTES IN COMPUTER SCIENCE, Vol.2528, 370~371, 2002.
- Web-based Intelligent Call Center for an Intensive Care Unit, LECTURE NOTES IN ARTIFICIAL INTELLIGENCE, Vol.2198, 530~539, 2001.
- Agent를 기반으로 한 지능형 호출 시스템, 정보과학회논문지(A/B/C), 7권, 5호, 522~538, 2001.
- 시뮬레이션을 이용한 소프트 핸드오프 방식의 성능 분석, 정보과학회논문지(A/B/C), 6권, 4호, 411~420, 2000.
- RNA 구조 예측을 위한 컴퓨터 모델링, 정보과학회논문지(A/B/C), 18권, 8호, 55~62, 2000.
- Mobile PC에서 다중 매체의 전송 및 재생을 지원하는 Virtual World 인터페이스의 개발, TELECOMMUNICATIONS REVIEW, Vol.10,No.4, 749~761, 2000.
- A Graphical Tool for Parametric Simulation of the RNA Structure Formation, MOLECULES AND CELLS, Vol.10, No.3, 348~355, 2000.
- 운전자 교육을 위한 PC 기반의 굴삭기 시뮬레이터의 개발, 국내공인학술지(이전), 9권,1호, 83~91, 2000.
- RNA 이차 구조의 시각화와 편집, 국내공인학술지(이전), 26권, 5호, 539~548, 1999.
- A vector-based method for drawing RNA secondary structure, 국제공인학술지(이전), Vol.15, No.4, 286~297, 1999.
- QFolder: RNA 분자 구조 형성 과정을 모의실험하기 위한 통합 시스템, 국내공인학술지(이전), 25권, 9호, 1389~1398, 1998.
- 컴퓨터 시뮬레이션을 이용한 이동통신 시스템의 Handoff 성능 분석, 대학논문, 2집, 9~14, 1998.
- 위성 운용 시스템의 실시간 처리 성능 분석, 대학논문, 26집, 107~123, 1998.
- 운동하는 물체를 위한 모델 구성과 시뮬레이션의 자동화, 국내공인학술지(이전), 23권, 7호, 699~710, 1996.
- Physical Map Construction by Ordering Random Genomic Clones, 국제공인학술지(이전), Vol.6, No.1, 45~50, 1996.
- 컴퓨터 모델링을 이용한 RNA 분자의 이차 구조 예측, 국내공인학술지(이전), 23권, 1호, 75~84, 1996.
- RNA 구조 형성 과정 추론의 자동화, 국제공인학술지(이전), Vol. 5, No.5, 406~412, 1995.
- Prediction of Common Folding Structures of Homologous RNAs, 국제공인학술지(이전), Vol.21, No.5, 1251~1257, 1993.
- Knowledge Specification of an Expert System, 국제공인학술지(이전), Vol.5, No.4, 29~38, 1990.

주요학술저서

- Advanced Intelligent Computing Theories and Applications, Springer, 2015.
- Intelligent Computing in Bioinformatics, Springer, 2014.
- Bio-Inspired Computing and Applications, Springer, 2011.
- Sequence and Genome Analytics: Methods and Applications, iConcept Press, 2011.

특허

- 결합 상대방을 고려하여 DNA 서열에서 단백질과 결합하는 부위를 예측하는 방법(Method for predicting protein-binding sites in a DNA sequence with consideration of binding partners), 2016.
- 결합 상대방을 고려하여 DNA 서열에서 단백질과 결합하는 부위를 예측하는 방법, 2014.
- 결합 상대방을 고려하여 RNA 서열에서 단백질과 결합하는 부위를 예측하는 방법, 2014.
- 특징 벡터에 기반한 훈련 데이터의 중복 제거 방법(FEATURE VECTOR-BASED METHOD FOR REMOVING REDUNDANCY IN A TRAINING DATASET), 2013.
- 온톨로지 기반의 단백질 상호작용 검색 엔진(An ontology based search engine for protein-protein interactions), 2012.
- Visualization method of RNA pseudoknot structures, 2011.
- Multimedia Communication Method using Virtual World Interface in Mobile Personal Computers, 2008.
- 단백질-알엔에이 복합체로부터 알엔에이 이차구조 추출 및 시각화 방법 및 시스템, 2007.
- Method for Visualizing Large-Scale Protein Interaction Data, 2007.
- DNA 이차구조의 시각화 방법(Method for Visualizing DNA Secondary Structures), 2007.
- Visualization method of RNA pseudoknot structures, 2006.
- 알엔에이(RNA) 슈도노트(Pseudoknot) 구조의시각화 방법(Visualization method of RNA Pseudoknot structures), 2006.
- 알앤에이(RNA) 슈도노트(Pseudoknot) 구조의시각화 방법(Visualization Method of RNA Pseudoknot Structures), 2006.
- Multimedia Communication Method using Virtual World Interface in Mobile Personal Computers, 2006.
- 단백질 상호작용 네트웍의 분할 시각화 기법, 2005.
- 단백질 상호작용 네트워크의 시각화방법, 2005.
- 대규모 단백질 상호작용 데이터의 효율적 시각화 기법, 2005.
- A vector-based method for visualizing secondary st, 2003.
- 휴대형 정보기기의 다중매체 전송 및 재생 방법, 2002.
- 벡터를 이용한 RNA 분자 이차구조의 시각화, 2001.
- 성장과정 모의실험을 통한 RNA 분자의 이차구조 예측 방법, 2001.